0090076
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Diazepam and Nordiazepam

DIAZ
Example Reports
High
Low
Normal

Ordering Recommendation

Use to optimize dosing and monitor patient adherence.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Timing of specimen collection: Predose (trough) draw at steady state concentration

Collect

Gray (potassium oxalate/sodium fluoride). Also acceptable: Plain red, green (sodium heparin), lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP standard transport tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Gel separator tubes. Plasma or whole blood collected in light blue (sodium citrate). Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years (Avoid repeated freeze/thaw cycles)

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Tue, Fri

Reported

1-7 days

Reference Interval

Dose-Related Range:

Test Number
 Components
 Dose-Related Range
  Diazepam Effective November 16, 2015
200-1000 ng/mL - Based on normal dosage amounts
  Nordiazepam Effective November 16, 2015
100-1500 ng/mL - Based on normal dosage amounts
Toxic: Greater than 2500 ng/mL

Interpretive Data

Adverse effects may include drowsiness, fatigue, ataxia, and muscle weakness.

Compliance Category

Standard

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
11/13/2023
X
N/A

CPT Codes

80346 (Alt code: G0480)

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Components

Component Test Code* Component Chart Name LOINC
0090075 Diazepam 3548-5
0090195 Nordiazepam 3537-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Benzodiazepines
  • Clorazepate
  • Diastat
  • Diazemuls
  • Diazepam and Metabolite
  • Nordiazepam
  • Stesolid
  • T-Quil
  • Tranxene
  • Valium
  • Valrelease
  • Zetran
Diazepam and Nordiazepam